abstract：BACKGROUND:The most recent published guidelines regarding management of patients surviving an acute myocardial infarction (AMI) advocate the administration of aspirin (ASA), beta blockers (BB), and angiotensin-converting enzyme inhibitors (ACEi) and discourages the use of calcium-channel blockers (CCB). Previous data c...

journal_title：Clinical cardiology

authors： Axtell SS,Ludwig E,Lope-Candales P

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND AND HYPOTHESIS:Previous research has failed to document temporal changes in epinephrine levels in patients with neurally mediated syncope associated with exercise. The purpose of this study was to investigate the role of circulatory catecholamines in exercise-induced neurally mediated syncope, specifically f...

journal_title：Clinical cardiology

authors： Takase B,Kastushika S,Hamabe A,Uehata A,Isojima K,Satomura K,Nishioka T,Ohsuzu F,Kurita A

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Epidemiologic evidence suggests that an elevated heart rate (HR) is an adverse and independent prognostic factor in arterial hypertension and other cardiovascular diseases. Although diltiazem is characterized as an HR-lowering calcium antagonist, no studies have quantified the magnitude of HR changes in pati...

journal_title：Clinical cardiology

authors： Boden WE,Vray M,Eschwege E,Lauret D,Scheldewaert R

更新日期：2001-01-01 00:00:00

abstract：:Despite a totality of evidence indicating clear benefits of statin therapy in secondary and primary prevention of cardiovascular disease (CVD), a large number of additional trials are currently planned or in progress to help us better understand, treat, and prevent CVD. Both monotherapy and combination statin regimens...

journal_title：Clinical cardiology

authors： Pfeffer MA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Advanced age remains one of the principal determinants of mortality in patients with acute myocardial infarction (AMI). HYPOTHESIS:The aim of this study was to determine the in-hospital outcome of elderly (> 75 years) patients with AMI who were admitted to hospitals participating in the national MITRA (Maxi...

journal_title：Clinical cardiology

authors： Haase KK,Schiele R,Wagner S,Fischer F,Burczyk U,Zahn R,Schuster S,Senges J

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Troponin I (TnI) is increasingly employed as a highly specific marker of acute myocardial ischemia. The value of this marker after cardiac surgery is unclear. HYPOTHESIS:The purpose of this study was to measure serum TnI levels prospectively at 1, 6, and 72 h after elective cardiac operations. In addition, ...

journal_title：Clinical cardiology

authors： Horvath KA,Parker MA,Frederiksen JW,Palmer AS,Fullerton DA

更新日期：2000-10-01 00:00:00

abstract：:Several investigators have documented the successful use of oral sustained-release theophylline in treating symptomatic bradycardia and sick sinus syndrome. This paper reports a case of chronotropic incompetence in which specific exercise indices, including the chronotropic response index, were used to measure the the...

journal_title：Clinical cardiology

authors： Dixon WC 4th,Bauch TD

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Cibenzoline, a class Ia antiarrhythmic drug, can be used to relieve left ventricular (LV) outflow obstruction in hypertrophic obstructive cardiomyopathy (HOCM). However, the mechanism of this agent in HOCM has been controversial. HYPOTHESIS:This study was designed to investigate the effect of cibenzoline on...

journal_title：Clinical cardiology

authors： Kondo I,Mizushige K,Nozaki S,Hirao K,Iwado Y,Ohmori K,Matsuo H

更新日期：2000-09-01 00:00:00

abstract：:Dobutamine stress echocardiography (DSE) is a reliable cardiac risk stratifier that has widespread applicability because of its clinical accuracy and cost effectiveness. Dobutamine has positive inotropic and chronotropic effects and is commonly used in patients who cannot exercise or achieve an adequate heart rate res...

journal_title：Clinical cardiology

authors： Usher BW Jr,O'Brien TX

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND HYPOTHESIS:Genetic influence on development of athlete's heart is uncertain. This study investigated whether angiotensin-converting enzyme (ACE) gene polymorphism influenced development of athlete's heart. METHODS:Forty-three participants in a 100-km ultramarathon were classified on the basis of ACE gen...

journal_title：Clinical cardiology

authors： Nagashima J,Musha H,Takada H,Awaya T,Oba H,Mori N,Ohmiya K,Nobuoka S,Murayama M

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Transesophageal echocardiography (TEE) has been used to identify the potential risk for cardiogenic embolism in patients with atrial fibrillation (AF). However, ischemic stroke in patients with AF is not always attributable to embolism. Identification of the risk of embolic versus atherothrombotic stroke sho...

journal_title：Clinical cardiology

authors： Shinokawa N,Hirai T,Takashima S,Kameyama T,Obata Y,Nakagawa K,Asanoi H,Inoue H

更新日期：2000-07-01 00:00:00

abstract：:Therapy with an angiotensin-converting enzyme (ACE) inhibitor is established for reducing excessive blood pressure, reducing mortality in patients with congestive heart failure (CHF), preventing the development of CHF in patients with asymptomatic left ventricular (LV) dysfunction, and preventing death and CHF when in...

journal_title：Clinical cardiology

authors： Pitt B

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Although suppression of premature ventricular contractions (PVCs) is not a predictor of mortality over the long term, the extent of PVC suppression is an important characteristic of any antiarrhythmic drug. HYPOTHESIS:This study was undertaken to determine whether intravenous (i.v.) dofetilide has the abili...

journal_title：Clinical cardiology

authors： Pool PE,Singh SN,Friedrich T

更新日期：2000-06-01 00:00:00

abstract：:Angina pectoris usually occurs in patients with significant coronary artery disease during periods of increased coronary demand such as increased heart rate. Bradycardia is a rare and unusal cause of angina pectoris that should be considered during the evaluation of patients with agnia. This paper reports three cases ...

journal_title：Clinical cardiology

authors： Shaheen J,Wanderman A,Tzivoni D

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:In many cardiac catheterization laboratories interventional procedures are performed at a date later than the diagnostic study, causing increased hospital days and costs. Few data exist which compare procedural success, complications, and costs between procedures performed at the time of diagnostic study and...

journal_title：Clinical cardiology

authors： Panchamukhi VB,Flaker GC

更新日期：2000-05-01 00:00:00

abstract：:Stress echocardiography is a widely applied technique for the evaluation of individuals with known or suspected coronary artery disease. The technique combines echocardiographic imaging with exercise testing or pharmacologic stress. Advances in digital image acquisition and harmonic imaging have substantially improved...

journal_title：Clinical cardiology

authors： Lewis JF

更新日期：2000-04-01 00:00:00

abstract：:The coronary sinus (CS) is a small tubular structure just above the posterior left atrioventricular junction. The CS can be imaged in several different echocardiographic views. Using zoom M-mode recordings of the CS in apical two-chamber view, CS caliber can be sharply imaged and easily measured during different phase...

journal_title：Clinical cardiology

authors： D'Cruz IA,Shala MB,Johns C

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Stimulated endothelium-derived relaxing factor-mediated vasodilation and conduit artery distensibility are impaired in congestive heart failure (CHF). L-arginine could have a potentially beneficial role in CHF, acting through the nitric oxide (NO)-L-arginine pathway or by growth hormone increment. HYPOTHESI...

journal_title：Clinical cardiology

authors： Bocchi EA,Vilella de Moraes AV,Esteves-Filho A,Bacal F,Auler JO,Carmona MJ,Bellotti G,Ramires AF

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Late potentials (LP) on signal-averaged electrocardiography (SAECG), recorded 6 to 30 days after an acute myocardial infarction (AMI), identify patients at risk for late arrhythmic events. Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce ventricular remodeling and cardiovascular morta...

journal_title：Clinical cardiology

authors： Chiladakis JA,Karapanos G,Agelopoulos G,Alexopoulos D,Manolis AS

更新日期：2000-02-01 00:00:00

abstract：:Rapid assessment of patients presenting with acute chest pain is essential, in order to distinguish between those who have a life-threatening condition, such as myocardial infarction or unstable angina, and the substantial proportion who do not have an acute coronary syndrome. It is thus of vital importance that relia...

journal_title：Clinical cardiology

authors： Husted SE

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Early reperfusion improves left ventricular (LV) function and survival after acute myocardial infarction (MI). Thrombolytic therapy achieves early patency of the infarct artery in about two-thirds of patients. In nearly half of the remaining patients, in whom early reperfusion was not achieved with thromboly...

journal_title：Clinical cardiology

authors： Ishihara M,Sato H,Tateishi H,Kawagoe T,Shimatani Y,Ueda K,Noma K,Yumoto A,Nishioka K

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Right ventricular dysfunction occurs in many patients with significant pulmonary valve regurgitation late after initial total repair of tetralogy of Fallot. Methods to predict which of these patients are at increased risk of late morbidity and mortality are not yet known. HYPOTHESIS:This study evaluated ele...

journal_title：Clinical cardiology

authors： Book WM,Parks WJ,Hopkins KL,Hurst JW

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The global T-inversion (GTI) electrocardiogram (ECG) is strikingly abnormal with major QTc prolongation, but with a surprisingly good prognosis by Kaplan-Meier curve. This contrasts with most significant QTc prolongations. HYPOTHESIS:This study was undertaken to ascertain QT interval dispersion (QTd) in glo...

journal_title：Clinical cardiology

authors： Desai SA,Mehrok S,Spodick DH

更新日期：1999-10-01 00:00:00

abstract：:Recent investigations have indicated that chronic heart failure can be reversed with agents that inhibit the reninangiotensin-aldosterone or sympathetic nervous system, such as angiontensin-converting enzyme (ACE) inhibitors and beta blockers. A meta-analysis of clinical trials of ACE inhibition in chronic heart failu...

journal_title：Clinical cardiology

authors： Eichhorn EJ

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:The presence or absence of collateral circulation to the infarct-related coronary artery in acute myocardial infarction (AMI) significantly impacts on infarct size and resulting left ventricular function. However, the determinants of collateral development have not been clarified. HYPOTHESIS:The purpose of ...

journal_title：Clinical cardiology

authors： Fujita M,Nakae I,Kihara Y,Hasegawa K,Nohara R,Ueda K,Tamaki S,Otsuka K,Sasayama S

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:QT interval shortens with exercise. Some of this shortening is due to an increase in heart rate, and some is due to other effects of exercise, probably mostly neuroendocrine effects. Data from subjects with cardiac transplants have suggested that non-heart rate-related changes in QT interval on exercise are ...

journal_title：Clinical cardiology

authors： Davey P,Bateman J

更新日期：1999-08-01 00:00:00

abstract：:Therapy for acute myocardial infarction has advanced dramatically since the early 1980s with the use of early intravenous fibrinolytic therapy. Combining low-dose fibrinolysis and platelet lysis appears to provide an additional increase in infarct-related artery (IRA) patency, but the large-scale mortality reduction t...

journal_title：Clinical cardiology

authors： Gassler JP,Topol EJ

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND HYPOTHESIS:Although it is well established that diabetes mellitus (DM) induces more severe coronary artery disease (CAD), it is not known whether it contributes to the development of coronary collateral circulation. The present study examines coronary collateral circulation in diabetic and nondiabetic pa...

journal_title：Clinical cardiology

authors： Melidonis A,Tournis S,Kouvaras G,Baltaretsou E,Hadanis S,Hajissavas I,Tsatsoulis A,Foussas S

更新日期：1999-07-01 00:00:00

abstract：:In the past, many have avoided nuts because of their high fat content. The Dietary Approaches to Stop Hypertension (DASH) diet, however, recommends regular consumption of this food along with seeds and dried beans (4-5 servings per week) as part of a diet to control hypertension. Nuts are nutrient-dense and most of th...

journal_title：Clinical cardiology

authors： Fraser GE

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:ST-segment depression during exercise testing is frequently observed in the absence of restenosis after percutaneous transluminal coronary angioplasty (PTCA). HYPOTHESIS:With the goal of improving the prediction of restenosis after PTCA, we evaluated the usefulness of ST-segment depression plus QT dispersio...

journal_title：Clinical cardiology

authors： Aytemir K,Ozer N,Aksöyek S,Ozkutlu H,Oto A,Ozmen F

更新日期：1999-06-01 00:00:00

abstract：:Triglyceride (TG) has long been associated as a risk factor for coronary artery disease. A recent meta-analysis of various epidemiologic studies has confirmed this link. An important issue is to assess further the appropriate cutpoints to classify desirable TG because recent data indicate that levels < 200 mg/dl confe...

journal_title：Clinical cardiology

authors： Miller M

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Syndrome X is defined as typical angina pectoris, positive treadmill exercise test, negative intravenous ergonovine test, and angiographically normal coronary arteries. HYPOTHESIS:In the present study, we investigated the anti-ischemic and antianginal effects of nisoldipine and ramipril in patients with syn...

journal_title：Clinical cardiology

authors： Ozçelik F,Altun A,Ozbay G

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The majority of coronary cameral fistulas (CCFs) are congenital in origin. On the other hand, acquired coronary cameral fistulas, having various etiopathogenic origins, are increasingly recognized. HYPOTHESIS:The aim of this study was to assess the possible involvement of coronary atherosclerosis in the pat...

journal_title：Clinical cardiology

authors： Said SA,van der Werf T

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:While depressed left ventricular ejection fraction is clearly associated with poor long-term outcome in heart failure (HF), the effect of ejection fraction on short-term outcomes and resource utilization following hospitalization for HF remains unclear. HYPOTHESIS:We evaluated the independent effect of depr...

journal_title：Clinical cardiology

authors： Harjai KJ,Nunez E,Turgut T,Shah MP,Humphrey JS,Newman J,Cheirif J,Smart FW,Ventura HO

更新日期：1999-03-01 00:00:00

abstract：:This report describes the case of a patient who developed postinfarction left ventricular free wall rupture and cardiac tamponade. He was managed conservatively, made a successful recovery, and is alive and asymptomatic 10 months after the index episode. Only 17 cases in which the patients survived subacute rupture of...

journal_title：Clinical cardiology

authors： Mathew TP,Johnston PW,Khan MM,Adgey AA

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Isolated left ventricular abnormal trabeculation (ILVAT) is defined as > 3 coarse trabeculations of the left ventricular wall, apically to the papillary muscles, in hearts without congenital malformations. HYPOTHESIS:The aims of the study were to assess by echocardiography the prevalence of ILVAT, to confir...

journal_title：Clinical cardiology

authors： Stöllberger C,Finsterer J,Valentin A,Blazek G,Tscholakoff D

更新日期：1999-02-01 00:00:00

abstract：:Until recently, instrumenting the pericardium was possible only when a pericardial effusion is present or by surgical exposure of the pericardium. Techniques are now being developed to instrument the normal pericardium. This development will allow clinicians and investigators to study pericardial fluid in health and i...

journal_title：Clinical cardiology

authors： Shabetai R

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:QT dispersion (QTd = QTmax-QTmin) measured as interlead variability of QT interval reflects the spatial inhomogeneity of ventricular repolarization times, and increased QTd may provide a substrate for malignant ventricular arrhythmias. Ischemia is associated with regional abnormalities of conduction and repo...

journal_title：Clinical cardiology

authors： Aytemir K,Bavafa V,Ozer N,Aksoyek S,Oto A,Ozmen F

更新日期：1999-01-01 00:00:00

abstract：:Natural history studies in heart failure have shown that increases in left ventricular (LV) volume and LV mass are directly related to future deterioration in LV performance and a less favorable clinical course. Despite the recognized importance of remodeling in heart failure, very little is known about the basic mech...

journal_title：Clinical cardiology

authors： Kurrelmeyer K,Kalra D,Bozkurt B,Wang F,Dibbs Z,Seta Y,Baumgarten G,Engle D,Sivasubramanian N,Mann DL

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Conventional approaches to management of congestive heart failure (CHF) rely on drugs that increase myocardial contractility or reduce ventricular afterload. These approaches often improve cardiac symptoms and survival, but may be associated with significant deleterious effects. An alternative approach is to...

journal_title：Clinical cardiology

authors： Lewis JF,DaCosta M,Wargowich T,Stacpoole P

更新日期：1998-12-01 00:00:00